DEVELOPMENT OF LENTIVIRAL VECTORS: IMPROVEMENT OF TRANSDUCTION EFFICIENCY, OF TRANSGENE EXPRESSION FEATURES, AND VALIDATION FOR GENE THERAPY APPLICATIONS BY DELIVERY OF THE FACTOR IX GENE INTO LIVER AND HEMATOPOIETIC STEM CELLS
- 3 Anni 1999/2002
- 139.443€ Totale Fondi
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Pubblicazioni Scientifiche
- 2003-02-01 HUMAN GENE THERAPY
Efficiency of onco-retroviral and lentiviral gene transfer into primary mouse and human B-lymphocytes is pseudotype dependent
- 2006-08-01 NATURE CELL BIOLOGY
SPPL2a and SPPL2b promote intramembrane proteolysis of TNFα in activated dendritic cells to trigger IL-12 production
- 2000-06-01 NATURE GENETICS
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
- 2003-06-01 NATURE MEDICINE
Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells
