INDENTIFICATION OF DOWNSTREAM TARGET GENES FOR THE HUMAN HOXD13 PROTEIN, INVOLVED IN SYNPOLYDACTYLY, USING A COMBINED CONDITIONAL EXPRESSION/PROMOTER TRAP APPROACH.

Pubblicazioni Scientifiche

• 2003-04-01 DEVELOPMENT

  An 147L substitution in the HOXD13 homeodomain causes a novel human limb malformation by producing a selective loss of function

• 2004-08-01 DEVELOPMENT

  Integration of anteroposterior and dorsoventral regulation of Phox2b transcription in cranial motoneuron progenitors by homeodomain proteins

• 2003-01-02 EMBO JOURNAL

  PBX1 nuclear export is regulated independently of PBX-MEINOX interaction by PKA phosphorylation of the PBC-B domain

• 1999-04-15 GENES & DEVELOPMENT

  The subcellular localization of PBX1 and EXD proteins depends on nuclear import and export signals and is modulated by association with PREP1 and HTH

• 2001-06-08 JOURNAL OF BIOLOGICAL CHEMISTRY

  The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function

• 1998-11-01 MOLECULAR AND CELLULAR BIOLOGY

  Definition of the transcriptional activation domains of three human HOX proteins depends on the DNA-binding context

• 2002-05-01 NUCLEIC ACIDS RESEARCH

  Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors

• 2004-10-12 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

  Cup is a nucleocytoplasmic shuttling protein that interacts with the eukaryotic translation initiation factor 4E to modulate Drosophila ovary development