STUDY OF THE MECHANISMS OF AMYLOID FORMATION

Pubblicazioni Scientifiche

• 2002-03-01 ELECTROPHORESIS

  Capillary electrophoresis investigation of a partially unfolded conformation of β2-microglobulin

• 2001-10-05 JOURNAL OF BIOLOGICAL CHEMISTRY

  Folding and aggregation are selectively influenced by the conformational preferences of the α-helices of muscle acylphosphatase

• 2001-12-14 JOURNAL OF BIOLOGICAL CHEMISTRY

  A partially structured species of β2-microglobulin is significantly populated under physiological conditions and involved in fibrillogenesis

• 2001-03-16 JOURNAL OF MOLECULAR BIOLOGY

  Detection of two partially structured species in the folding process of the amyloidogenic protein β2-microglobulin

• 2002-04-04 NATURE

  Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

• 2002-02-01 NATURE STRUCTURAL BIOLOGY

  Kinetic partitioning of protein folding and aggregation

• 2002-12-10 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

  Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases

• 2001-04-01 PROTEIN SCIENCE

  Reduction of the amyloidogenicity of a protein by specific binding of ligands to the native conformation

• 2001-12-01 PROTEIN SCIENCE

  Solution conditions can promote formation of either amyloid protofilaments or mature fibrils from the HypF N-terminal domain